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When dealing with weight-loss and the people who go through it you need to err along the side of caution and let the FDA do its job and demand some research be done so the public understands the side effects and hazards of the medications before we take them. Keep in mind that drug companies have been in business to make money and that they would say almost anything to keep people on their own medications. Researchers found out that participants taking this drug for a year, dropped a few pounds within four weeks and have kept the weight off during the entire 56 weeks from the study. Contrave is really a combination of the drugs naltrexone and bupropion, which usually reflect a brand new trend of weight-loss drugs which are made up of more than one active ingredient, which might make them far better and safer. 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Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise hypertension and heart rate and must stop used in patients with uncontrolled high blood pressure level, along with by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients with a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients to the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking. "There were no signs of depression or suicidal thoughts in trial participants," said Fujioka.

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